Autophagic cell death restricts chromosomal instability during replicative crisis
Autophagic cell death restricts chromosomal instability during replicative crisis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Replicative crisis is a senescence-independent process that acts as a final barrier against oncogenic transformation by eliminating pre-cancerous cells with disrupted cell cycle checkpoints
1
. It functions as a potent tumour suppressor and culminates in extensive cell death. Cells rarely evade elimination and evolve towards malignancy, but t...
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Full title
Autophagic cell death restricts chromosomal instability during replicative crisis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6557118
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6557118
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-0885-0
