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PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6563913

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

About this item

Full title

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-10, Vol.362 (6413), p.464-467

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Activation of stretch-sensitive baroreceptor neurons exerts acute control over heart rate and blood pressure. Although this homeostatic baroreflex has been described for more than 80 years, the molecular identity of baroreceptor mechanosensitivity remains unknown. We discovered that mechanically activated ion channels PIEZO1 and PIEZO2 are together...

Alternative Titles

Full title

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6563913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6563913

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aau6324

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