Recombinant production, purification, crystallization, and structure analysis of human transforming...
Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Transforming growth factor β is a disulfide-linked dimeric cytokine that occurs in three highly related isoforms (TGFβ1–TGFβ3) engaged in signaling functions through binding of cognate TGFβ receptors. To regulate this pathway, the cytokines are biosynthesized as inactive pro-TGFβs with an N-terminal latency-associated protein preceding the mature m...
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Full title
Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6572864
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6572864
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-44943-4
