Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by incr...
Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer’s disease model) using DNA microarray analysis and revealed that the dopamine (DA)-signaling pathway was enhanced in the group fed RA versus controls. In the cerebral cortex, the lev...
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Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6581955
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6581955
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-45168-1