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Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6600269

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

About this item

Full title

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2019-06, Vol.20 (11), p.2703

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels in macrophages significantly affect their polarization phenotype and consequently atherosclerosis in mice. Moreover, the activit...

Alternative Titles

Full title

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6600269

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6600269

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms20112703

How to access this item