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Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6601006

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

About this item

Full title

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.13097-13106

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new synapses formed at the time of learning upon neuronal network activation depends on the stress hormone-activated glucocorticoid receptor (GR) and neurotrophic factor release. Whether and how c...

Alternative Titles

Full title

Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6601006

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6601006

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1903203116

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