Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis
Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis
About this item
Full title
Author / Creator
Zhao, Lan , Huang, Jian , Fan, Yunshan , Li, Jun , You, Tianming , He, Shisheng , Xiao, Guozhi and Chen, Di
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Subjects
More information
Scope and Contents
Contents
ObjectivesOsteoarthritis (OA) is a painful and debilitating disease and it is associated with aberrant upregulation of multiple factors, including matrix metalloproteinase 13 (MMP13), interleukin-1β (IL-1β) and nerve growth factor (NGF). In this study, we aimed to use the CRISPR/Cas9 technology, a highly efficient gene-editing tool, to study whethe...
Alternative Titles
Full title
Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6621547
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6621547
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2018-214724
