The Beneficial Roles of SIRT1 in Drug-Induced Liver Injury
The Beneficial Roles of SIRT1 in Drug-Induced Liver Injury
About this item
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Author / Creator
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Scope and Contents
Contents
Drug-induced liver injury (DILI) is a major cause of acute liver failure (ALF) as a result of accumulated drugs in the human body metabolized into toxic agents and helps generate heavy oxidative stress, inflammation, and apoptosis, which induces necrosis in hepatocytes and ultimately damages the liver. Sirtuin 1 (SIRT1) is said to have multiple vit...
Alternative Titles
Full title
The Beneficial Roles of SIRT1 in Drug-Induced Liver Injury
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6636535
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6636535
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2019/8506195
