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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6637939

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

About this item

Full title

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2018-02, Vol.378 (5), p.449-459

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

CAR T cells expressing anti-CD19 and signaling molecules CD28 and CD3-zeta chain induced complete remission in 83% of patients with refractory ALL. Patients with a low disease burden had longer survival and a lower rate of toxic effects than those with a high disease burden.

Alternative Titles

Full title

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6637939

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6637939

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1709919

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