Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Rationale
Alcohol use disorder (AUD) involves dysregulation of innate immune signaling in brain. Toll-like receptor 3 (TLR3), an innate immune receptor that is upregulated in post-mortem human alcoholics, leads to induction of interferon (IFN) signaling. IFNs have been linked to depressive-like symptoms and therefore may play a role in addiction...
Alternative Titles
Full title
Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6646093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6646093
Other Identifiers
ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-018-5153-8
