Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy
Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy
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Publisher
Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Contents
Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME): tumor blood vessels and cells of the immune system. It damages endothelial cells and causes radiation-induced inflammation. Damaged vessels inhibit the infiltration of CD8+ T lymphocytes into tumors, and immunosuppressive pathways are activated. They lead to the...
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Full title
Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650939
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650939
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms20133212