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Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy

Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650939

Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy

About this item

Full title

Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2019-06, Vol.20 (13), p.3212

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME): tumor blood vessels and cells of the immune system. It damages endothelial cells and causes radiation-induced inflammation. Damaged vessels inhibit the infiltration of CD8+ T lymphocytes into tumors, and immunosuppressive pathways are activated. They lead to the...

Alternative Titles

Full title

Tumor Microenvironment as A "Game Changer" in Cancer Radiotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650939

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650939

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms20133212

How to access this item