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The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650959

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

About this item

Full title

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3318

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Psoriasis is an immune-mediated inflammatory skin disease that involves mainly T helper (Th)17, Th1 and Th22 lymphocytes, which cause hyper-proliferation of the epidermis with aberrant differentiation of keratinocytes, and local production of chemokines and cytokines. These fuel a self-amplifying loop where these products act on T cells to perpetua...

Alternative Titles

Full title

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650959

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6650959

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms20133318

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