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Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659742

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

About this item

Full title

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6416), p.839-842

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

CRISPR-Cas systems provide microbes with adaptive immunity to infectious nucleic acids and are widely employed as genome editing tools. These tools use RNA-guided Cas proteins whose large size (950 to 1400 amino acids) has been considered essential to their specific DNA- or RNA-targeting activities. Here we present a set of CRISPR-Cas systems from...

Alternative Titles

Full title

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6659742

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aav4294

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