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Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6660746

Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

About this item

Full title

Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.15013-15022

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Phosphorylation reactions, driven by competing kinases and phosphatases, are central elements of cellular signal transduction. We reconstituted a native eukaryotic lipid kinase–phosphatase reaction that drives the interconversion of phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-phosphate [PI(4,5)P₂] on membrane surfaces. Th...

Alternative Titles

Full title

Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6660746

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6660746

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1901744116

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