Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Abtract
Forkhead box A1 (FOXA1) is a pioneer transcription factor that is essential for the normal development of several endoderm-derived organs, including the prostate gland
1
,
2
. FOXA1 is frequently mutated in hormone-receptor-driven prostate, breast, bladder and salivary-gland tumours
3
–
8
. However, it is unclear...
Alternative Titles
Full title
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6661908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6661908
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1347-4
