Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients...
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer
About this item
Full title
Author / Creator
Yurgelun, Matthew B. , Chittenden, Anu B. , Morales-Oyarvide, Vicente , Rubinson, Douglas A. , Dunne, Richard F. , Kozak, Margaret M. , Qian, Zhi Rong , Welch, Marisa W. , Brais, Lauren K. , Da Silva, Annacarolina , Bui, Justin L. , Yuan, Chen , Li, Tingting , Li, Wanwan , Masuda, Atsuhiro , Gu, Mancang , Bullock, Andrea J. , Chang, Daniel T. , Clancy, Thomas E. , Linehan, David C. , Findeis-Hosey, Jennifer J. , Doyle, Leona A. , Thorner, Aaron R. , Ducar, Matthew D. , Wollison, Bruce M. , Khalaf, Natalia , Perez, Kimberly , Syngal, Sapna , Aguirre, Andrew J. , Hahn, William C. , Meyerson, Matthew L. , Fuchs, Charles S. , Ogino, Shuji , Hornick, Jason L. , Hezel, Aram F. , Koong, Albert C. , Nowak, Jonathan A. and Wolpin, Brian M.
Publisher
New York: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
New York: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
Germline variants in double-strand DNA damage repair (dsDDR) genes (e.g., BRCA1/2) predispose to pancreatic adenocarcinoma (PDAC) and may predict sensitivity to platinum-based chemotherapy and poly(ADP) ribose polymerase (PARP) inhibitors. We sought to determine the prevalence and significance of germline cancer susceptibility gene variants in PDAC...
Alternative Titles
Full title
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Chittenden, Anu B.
Morales-Oyarvide, Vicente
Rubinson, Douglas A.
Dunne, Richard F.
Kozak, Margaret M.
Qian, Zhi Rong
Welch, Marisa W.
Brais, Lauren K.
Da Silva, Annacarolina
Bui, Justin L.
Yuan, Chen
Li, Tingting
Li, Wanwan
Masuda, Atsuhiro
Gu, Mancang
Bullock, Andrea J.
Chang, Daniel T.
Clancy, Thomas E.
Linehan, David C.
Findeis-Hosey, Jennifer J.
Doyle, Leona A.
Thorner, Aaron R.
Ducar, Matthew D.
Wollison, Bruce M.
Khalaf, Natalia
Perez, Kimberly
Syngal, Sapna
Aguirre, Andrew J.
Hahn, William C.
Meyerson, Matthew L.
Fuchs, Charles S.
Ogino, Shuji
Hornick, Jason L.
Hezel, Aram F.
Koong, Albert C.
Nowak, Jonathan A.
Wolpin, Brian M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6666401
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6666401
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/s41436-018-0009-5
