Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Pericytes are positioned between brain capillary endothelial cells, astrocytes and neurons. They degenerate in multiple neurological disorders. However, their role in the pathogenesis of these disorders remains debatable. Here we generate an inducible pericyte-specific Cre line and cross pericyte-specific Cre mice with iDTR mice carrying Cre-depend...
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Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668719
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668719
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-019-0434-z
