Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
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Author / Creator
Vladoiu, Maria C. , El-Hamamy, Ibrahim , Donovan, Laura K. , Farooq, Hamza , Holgado, Borja L. , Sundaravadanam, Yogi , Ramaswamy, Vijay , Hendrikse, Liam D. , Kumar, Sachin , Mack, Stephen C. , Lee, John J. Y. , Fong, Vernon , Juraschka, Kyle , Przelicki, David , Michealraj, Antony , Skowron, Patryk , Luu, Betty , Suzuki, Hiromichi , Morrissy, A. Sorana , Cavalli, Florence M. G. , Garzia, Livia , Daniels, Craig , Wu, Xiaochong , Qazi, Maleeha A. , Singh, Sheila K. , Chan, Jennifer A. , Marra, Marco A. , Malkin, David , Dirks, Peter , Heisler, Lawrence , Pugh, Trevor , Ng, Karen , Notta, Faiyaz , Thompson, Eric M. , Kleinman, Claudia L. , Joyner, Alexandra L. , Jabado, Nada , Stein, Lincoln and Taylor, Michael D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that change over the course of development. Here we use single-cell transcriptomics to study more than 60,000 cells from the developing mouse cerebellum and show that different molecular subgroups of childhood cerebell...
Alternative Titles
Full title
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Authors, Artists and Contributors
Author / Creator
El-Hamamy, Ibrahim
Donovan, Laura K.
Farooq, Hamza
Holgado, Borja L.
Sundaravadanam, Yogi
Ramaswamy, Vijay
Hendrikse, Liam D.
Kumar, Sachin
Mack, Stephen C.
Lee, John J. Y.
Fong, Vernon
Juraschka, Kyle
Przelicki, David
Michealraj, Antony
Skowron, Patryk
Luu, Betty
Suzuki, Hiromichi
Morrissy, A. Sorana
Cavalli, Florence M. G.
Garzia, Livia
Daniels, Craig
Wu, Xiaochong
Qazi, Maleeha A.
Singh, Sheila K.
Chan, Jennifer A.
Marra, Marco A.
Malkin, David
Dirks, Peter
Heisler, Lawrence
Pugh, Trevor
Ng, Karen
Notta, Faiyaz
Thompson, Eric M.
Kleinman, Claudia L.
Joyner, Alexandra L.
Jabado, Nada
Stein, Lincoln
Taylor, Michael D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6675628
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6675628
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1158-7