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Childhood cerebellar tumours mirror conserved fetal transcriptional programs

Childhood cerebellar tumours mirror conserved fetal transcriptional programs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6675628

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that change over the course of development. Here we use single-cell transcriptomics to study more than 60,000 cells from the developing mouse cerebellum and show that different molecular subgroups of childhood cerebell...

Alternative Titles

Full title

Childhood cerebellar tumours mirror conserved fetal transcriptional programs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6675628

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6675628

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1158-7

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