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Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk varia...

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk varia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6677164

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

About this item

Full title

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2019-08, Vol.51 (8), p.1252-1262

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Mutations in gene regulatory elements have been associated with a wide range of complex neuropsychiatric disorders. However, due to their cell-type specificity and difficulties in characterizing their regulatory targets, the ability to identify causal genetic variants has remained limited. To address these constraints, we perform an integrative ana...

Alternative Titles

Full title

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6677164

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6677164

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-019-0472-1

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