miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease
miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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A major hallmark of Parkinson’s disease (PD) is the degeneration of dopaminergic neurons in the substantia nigra, and the causative mechanism is thought to be the activation of programmed neuronal death. Necroptosis is a regulated process of cell death triggered by RIPK1. Although the pathophysiology of PD has been studied extensively, the cellular...
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Full title
miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6683159
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6683159
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-019-1809-5
