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Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690029

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

About this item

Full title

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.16046-16055

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Epstein–Barr virus (EBV) is a human tumor virus and a model of herpesviral latency. The virus efficiently infects resting human B lymphocytes and induces their continuous proliferation in vitro, which mimics certain aspects of EBV’s oncogenic potential in vivo. How lymphoblastoid cell lines (LCLs) evolve from the infected lymphocytes is uncertain....

Alternative Titles

Full title

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690029

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6690029

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1901314116

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