Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
About this item
Full title
Author / Creator
Wellenstein, Max D. , Coffelt, Seth B. , Duits, Danique E. M. , van Miltenburg, Martine H. , Slagter, Maarten , de Rink, Iris , Henneman, Linda , Kas, Sjors M. , Prekovic, Stefan , Hau, Cheei-Sing , Vrijland, Kim , Drenth, Anne Paulien , de Korte-Grimmerink, Renske , Schut, Eva , van der Heijden, Ingrid , Zwart, Wilbert , Wessels, Lodewyk F. A. , Schumacher, Ton N. , Jonkers, Jos and de Visser, Karin E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancer-associated systemic inflammation is strongly linked to poor disease outcome in patients with cancer
1
,
2
. For most human epithelial tumour types, high systemic neutrophil-to-lymphocyte ratios are associated with poor overall survival
3
, and experimental studies have demonstrated a causal relationship between neutrophils...
Alternative Titles
Full title
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
Authors, Artists and Contributors
Author / Creator
Coffelt, Seth B.
Duits, Danique E. M.
van Miltenburg, Martine H.
Slagter, Maarten
de Rink, Iris
Henneman, Linda
Kas, Sjors M.
Prekovic, Stefan
Hau, Cheei-Sing
Vrijland, Kim
Drenth, Anne Paulien
de Korte-Grimmerink, Renske
Schut, Eva
van der Heijden, Ingrid
Zwart, Wilbert
Wessels, Lodewyk F. A.
Schumacher, Ton N.
Jonkers, Jos
de Visser, Karin E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707815
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1450-6
