Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lym...
Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lymphoma cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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p97 is an ATPase that works in concert with histone deacetylase 6 (HDAC6), to facilitate the degradation of misfolded proteins by autophagosomes. p97 has also been implicated in DNA repair and maintaining genomic stability. In this study, we determined the effect of combined inhibition of p97 and HDAC6 activities in mantle cell lymphoma (MCL) cells...
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Full title
Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lymphoma cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6730676
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6730676
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-018-0355-y
