Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclei...
Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Many neurodegenerative diseases are characterized by the accumulation of abnormal protein aggregates in the brain. In Parkinson’s disease (PD), α-synuclein (α-syn) forms such aggregates called Lewy bodies (LBs). Recently, it has been reported that aggregates of α-syn with a cross-β structure are capable of propagating within the brain in a prionlik...
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Full title
Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6731630
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6731630
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1906124116
