Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disord...
Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD) might be caused by a reduction in signal-to-noise in key neural circuits, which could be the result of changes in excitatory-inhibitory (E-I) balance. Here, we have clarified the concept of E-I balance, and updated the original hypothesis in light of the field’s increasin...
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Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6742424
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6742424
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-019-0426-0
