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Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6746989

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

About this item

Full title

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-09, Vol.9 (1), p.13342-12, Article 13342

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Vascular endothelial growth factor receptor-2 (VEGFR2) and its ligands (VEGFs) are crucial players in vasculogenesis and angiogenesis. General blocking of this signaling system with antibodies or small molecule inhibitors is an established strategy to treat cancer and age-related macular degeneration. Nevertheless, the activated receptor can signal...

Alternative Titles

Full title

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6746989

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6746989

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-49646-4

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