Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Vascular endothelial growth factor receptor-2 (VEGFR2) and its ligands (VEGFs) are crucial players in vasculogenesis and angiogenesis. General blocking of this signaling system with antibodies or small molecule inhibitors is an established strategy to treat cancer and age-related macular degeneration. Nevertheless, the activated receptor can signal...
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Full title
Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6746989
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6746989
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49646-4