GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells
About this item
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Author / Creator
Pintado-Berninches, Laura , Fernandez-Varas, Beatriz , Benitez-Buelga, Carlos , Manguan-Garcia, Cristina , Serrano-Benitez, Almudena , Iarriccio, Laura , Carrillo, Jaime , Guenechea, Guillermo , Egusquiaguirre, Susana P. , Pedraz, Jose-Luis , Hernández, Rosa M. , Igartua, Manoli , Arias-Salgado, Elena G. , Cortés-Ledesma, Felipe , Sastre, Leandro and Perona, Rosario
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Ataxia telangiectasia (AT) is a genetic disease caused by mutations in the
ATM
gene but the mechanisms underlying AT are not completely understood. Key functions of the ATM protein are to sense and regulate cellular redox status and to transduce DNA double-strand break signals to downstream effectors. ATM-deficient cells show increased ROS ac...
Alternative Titles
Full title
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells
Authors, Artists and Contributors
Author / Creator
Fernandez-Varas, Beatriz
Benitez-Buelga, Carlos
Manguan-Garcia, Cristina
Serrano-Benitez, Almudena
Iarriccio, Laura
Carrillo, Jaime
Guenechea, Guillermo
Egusquiaguirre, Susana P.
Pedraz, Jose-Luis
Hernández, Rosa M.
Igartua, Manoli
Arias-Salgado, Elena G.
Cortés-Ledesma, Felipe
Sastre, Leandro
Perona, Rosario
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6748109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6748109
Other Identifiers
ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/s41418-018-0272-7
