Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The serotonin transporter (SERT) regulates neurotransmitter homeostasis through the sodium- and chloride-dependent recycling of serotonin into presynaptic neurons
1
–
3
. Major depression and anxiety disorders are treated using selective serotonin reuptake inhibitors—small molecules that competitively block substrate binding and thereby...
Alternative Titles
Full title
Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6750207
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6750207
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1135-1
