Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
About this item
Full title
Author / Creator
Sakamoto, Yasumitsu , Suzuki, Yoshiyuki , Nakamura, Akihiro , Watanabe, Yurie , Sekiya, Mizuki , Roppongi, Saori , Kushibiki, Chisato , Iizuka, Ippei , Tani, Osamu , Sakashita, Hitoshi , Inaka, Koji , Tanaka, Hiroaki , Yamada, Mitsugu , Ohta, Kazunori , Honma, Nobuyuki , Shida, Yosuke , Ogasawara, Wataru , Nakanishi-Matsui, Mayumi , Nonaka, Takamasa , Gouda, Hiroaki and Tanaka, Nobutada
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Antimicrobial resistance is a global public threat and raises the need for development of new antibiotics with a novel mode of action. The dipeptidyl peptidase 11 from
Porphyromonas gingivalis
(PgDPP11) belongs to a new class of serine peptidases, family S46. Because S46 peptidases are not found in mammals, these enzymes are attractive target...
Alternative Titles
Full title
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
Authors, Artists and Contributors
Author / Creator
Suzuki, Yoshiyuki
Nakamura, Akihiro
Watanabe, Yurie
Sekiya, Mizuki
Roppongi, Saori
Kushibiki, Chisato
Iizuka, Ippei
Tani, Osamu
Sakashita, Hitoshi
Inaka, Koji
Tanaka, Hiroaki
Yamada, Mitsugu
Ohta, Kazunori
Honma, Nobuyuki
Shida, Yosuke
Ogasawara, Wataru
Nakanishi-Matsui, Mayumi
Nonaka, Takamasa
Gouda, Hiroaki
Tanaka, Nobutada
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6753110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6753110
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-49984-3
