Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and...
Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments
About this item
Full title
Author / Creator
Shen, Yaoqing , Grisdale, Cameron J. , Islam, Sumaiya A. , Bose, Pinaki , Lever, Jake , Zhao, Eric Y. , Grinshtein, Natalie , Ma, Yussanne , Mungall, Andrew J. , Moore, Richard A. , Lun, Xueqing , Senger, Donna L. , Robbins, Stephen M. , Wang, Alice Yijun , MacIsaac, Julia L. , Kobor, Michael S. , Luchman, H. Artee , Weiss, Samuel , Chan, Jennifer A. , Blough, Michael D. , Kaplan, David R. , Cairncross, J. Gregory , Marra, Marco A. and Jones, Steven J. M.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Glioblastoma multiforme (GBM) is the most deadly brain tumor, and currently lacks effective treatment options. Brain tumor-initiating cells (BTICs) and orthotopic xenografts are widely used in investigating GBM biology and new therapies for this aggressive disease. However, the genomic characteristics and molecular resemblance of these models to GB...
Alternative Titles
Full title
Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments
Authors, Artists and Contributors
Author / Creator
Grisdale, Cameron J.
Islam, Sumaiya A.
Bose, Pinaki
Lever, Jake
Zhao, Eric Y.
Grinshtein, Natalie
Ma, Yussanne
Mungall, Andrew J.
Moore, Richard A.
Lun, Xueqing
Senger, Donna L.
Robbins, Stephen M.
Wang, Alice Yijun
MacIsaac, Julia L.
Kobor, Michael S.
Luchman, H. Artee
Weiss, Samuel
Chan, Jennifer A.
Blough, Michael D.
Kaplan, David R.
Cairncross, J. Gregory
Marra, Marco A.
Jones, Steven J. M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6754609
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6754609
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1813495116
