The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic a...
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Perturbations to mammalian switch/sucrose non-fermentable (mSWI/SNF) chromatin remodeling complexes have been widely implicated as driving events in cancer
1
. One such perturbation is the dual loss of the SMARCA4 and SMARCA2 ATPase subunits in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT)
2
–
5
, SMARCA4-deficien...
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The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6755913
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6755913
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0363-5