Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technic...
Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS
About this item
Full title
Author / Creator
Scheijen, Blanca , Meijers, Ruud W. J. , Rijntjes, Jos , van der Klift, Michèle Y. , Möbs, Markus , Steinhilber, Julia , Reigl, Tomas , van den Brand, Michiel , Kotrová, Michaela , Ritter, Julia-Marie , Catherwood, Mark A. , Stamatopoulos, Kostas , Brüggemann, Monika , Davi, Frédéric , Darzentas, Nikos , Pott, Christiane , Fend, Falko , Hummel, Michael , Langerak, Anton W. , Groenen, Patricia J. T. A. , EuroClonality-NGS Working Group and on behalf of the EuroClonality-NGS Working Group
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
One of the hallmarks of B lymphoid malignancies is a B cell clone characterized by a unique footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic marker for clonality assessment. The EuroClonality/BIOMED-2 assay is currently the gold standard for analyzing IG heavy chain (IGH
)
and κ light chain (IGK) gene re...
Alternative Titles
Full title
Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS
Authors, Artists and Contributors
Author / Creator
Meijers, Ruud W. J.
Rijntjes, Jos
van der Klift, Michèle Y.
Möbs, Markus
Steinhilber, Julia
Reigl, Tomas
van den Brand, Michiel
Kotrová, Michaela
Ritter, Julia-Marie
Catherwood, Mark A.
Stamatopoulos, Kostas
Brüggemann, Monika
Davi, Frédéric
Darzentas, Nikos
Pott, Christiane
Fend, Falko
Hummel, Michael
Langerak, Anton W.
Groenen, Patricia J. T. A.
EuroClonality-NGS Working Group
on behalf of the EuroClonality-NGS Working Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756030
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-019-0508-7
