Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through...
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
About this item
Full title
Author / Creator
Richter, Melanie , Murtaza, Nadeem , Scharrenberg, Robin , White, Sean H. , Johanns, Ole , Walker, Susan , Yuen, Ryan K. C. , Schwanke, Birgit , Bedürftig, Bianca , Henis, Melad , Scharf, Sarah , Kraus, Vanessa , Dörk, Ronja , Hellmann, Jakob , Lindenmaier, Zsuzsa , Ellegood, Jacob , Hartung, Henrike , Kwan, Vickie , Sedlacik, Jan , Fiehler, Jens , Schweizer, Michaela , Lerch, Jason P. , Hanganu-Opatz, Ileana L. , Morellini, Fabio , Scherer, Stephen W. , Singh, Karun K. and Calderon de Anda, Froylan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Atypical brain connectivity is a major contributor to the pathophysiology of neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs).
TAOK2
is one of several genes in the 16p11.2 microdeletion region, but whether it contributes to NDDs is unknown. We performed behavioral analysis on
Taok2
heterozygous (Het) and kn...
Alternative Titles
Full title
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
Authors, Artists and Contributors
Author / Creator
Murtaza, Nadeem
Scharrenberg, Robin
White, Sean H.
Johanns, Ole
Walker, Susan
Yuen, Ryan K. C.
Schwanke, Birgit
Bedürftig, Bianca
Henis, Melad
Scharf, Sarah
Kraus, Vanessa
Dörk, Ronja
Hellmann, Jakob
Lindenmaier, Zsuzsa
Ellegood, Jacob
Hartung, Henrike
Kwan, Vickie
Sedlacik, Jan
Fiehler, Jens
Schweizer, Michaela
Lerch, Jason P.
Hanganu-Opatz, Ileana L.
Morellini, Fabio
Scherer, Stephen W.
Singh, Karun K.
Calderon de Anda, Froylan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6756231
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-018-0025-5
