Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model
Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Melanin pigment has a significant role in ocular pharmacokinetics, because many drugs bind at high extent to melanin in the retinal pigment epithelial cells. Most retinal pigment epithelial cell lines lack pigmentation and, therefore, we re-pigmented human ARPE-19 cells to generate a pigmented cell model. Melanosomes from porcine retinal pigment ep...
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Full title
Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6760193
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6760193
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-50324-8