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Systems structural biology measurements by in vivo cross-linking with mass spectrometry

Systems structural biology measurements by in vivo cross-linking with mass spectrometry

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6777709

Systems structural biology measurements by in vivo cross-linking with mass spectrometry

About this item

Full title

Systems structural biology measurements by in vivo cross-linking with mass spectrometry

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2019-08, Vol.14 (8), p.2318-2343

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This protocol describes a workflow for utilizing large-scale cross-linking with mass spectrometry (XL-MS) to make systems-level structural biology measurements in complex biological samples, including cells, isolated organelles, and tissue samples. XL-MS is a structural biology technique that provides information on the molecular structure of prote...

Alternative Titles

Full title

Systems structural biology measurements by in vivo cross-linking with mass spectrometry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6777709

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6777709

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/s41596-019-0181-3

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