3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Alzheimer’s disease (AD) is a progressive, neurodegenerative dementia with no cure. Prominent hypotheses suggest accumulation of beta-amyloid (Aβ) contributes to neurodegeneration and memory loss, however identifying brain regions with early susceptibility to Aβ remains elusive. Using SWITCH to immunolabel intact brain, we created a spatiotemporal...
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3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6778135
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6778135
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2399-3642
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2399-3642
DOI
10.1038/s42003-019-0599-8