IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Interleukin-1 receptor associated kinase 3 (IRAK3) is a cytoplasmic homeostatic mediator of inflammatory responses and is potentially useful as a prognostic marker in inflammation. IRAK3 inhibits signalling cascades downstream of myddosome complexes associated with toll like receptors. IRAK3 contains a death domain that interacts with other IRAK fa...
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Full title
IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6820782
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6820782
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-51913-3
