Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis
About this item
Full title
Author / Creator
Belavgeni, Alexia , Bornstein, Stefan R. , von Mässenhausen, Anne , Tonnus, Wulf , Stumpf, Julian , Meyer, Claudia , Othmar, Evelyn , Latk, Markus , Kanczkowski, Waldemar , Kroiss, Matthias , Hantel, Constanze , Hugo, Christian , Fassnacht, Martin , Ziegler, Christian G. , Schally, Andrew V. , Krone, Nils P. and Linkermann, Andreas
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Adrenocortical carcinomas (ACCs) are rare and highly malignant cancers associated with poor survival of patients. Currently, mitotane, a nonspecific derivative of the pesticide DDT (1,1-(dichlorobiphenyl)-2,2-dichloroethane), is used as the standard treatment, but its mechanism of action in ACCs remains elusive. Here we demonstrate that the human A...
Alternative Titles
Full title
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6825277
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6825277
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1912700116
