Somatic mutations and clonal dynamics in healthy and cirrhotic human liver
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The most common causes of chronic liver disease are excess alcohol intake, viral hepatitis and non-alcoholic fatty liver disease, with the clinical spectrum ranging in severity from hepatic inflammation to cirrhosis, liver failure or hepatocellular carcinoma (HCC). The genome of HCC exhibits diverse mutational signatures, resulting in recurrent mut...
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Full title
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6837891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6837891
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1670-9