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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6837891

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

About this item

Full title

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-10, Vol.574 (7779), p.538-542

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The most common causes of chronic liver disease are excess alcohol intake, viral hepatitis and non-alcoholic fatty liver disease, with the clinical spectrum ranging in severity from hepatic inflammation to cirrhosis, liver failure or hepatocellular carcinoma (HCC). The genome of HCC exhibits diverse mutational signatures, resulting in recurrent mut...

Alternative Titles

Full title

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6837891

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6837891

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1670-9

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