The mechanism of eukaryotic CMG helicase activation
The mechanism of eukaryotic CMG helicase activation
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
In vitro
experiments, using purified proteins and an assay that detects DNA unwinding, reveal the mechanism of activation of eukaryotic DNA replication.
Unravelling DNA replication
DNA replication in eukaryotes begins with the loading of a double hexamer of minichromosome maintenance (MCM) proteins onto the origin. Replication is then acti...
Alternative Titles
Full title
The mechanism of eukaryotic CMG helicase activation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6847044
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6847044
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25787
