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Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6859072

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

About this item

Full title

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2019-11, Vol.20 (11), p.1542-1554

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Quantitative mass spectrometry reveals how CD4
+
and CD8
+
T cells restructure proteomes in response to antigen and mammalian target of rapamycin complex 1 (mTORC1). Analysis of copy numbers per cell of >9,000 proteins provides new understanding of T cell phenotypes, exposing the metabolic and protein synthesis machinery and environment...

Alternative Titles

Full title

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6859072

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6859072

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0495-x

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