Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered...
Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Targeted delivery of lysosomal enzymes to the endocytic compartment of human cells represents a transformative technology for treating a large family of lysosomal storage diseases (LSDs). Gaucher disease is one of the most common types of LSDs caused by mutations to the lysosomal β-glucocerebrosidase (GBA). Here, we describe a genetic strategy to p...
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Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6872767
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6872767
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-53844-5
