Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the r...
Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina
About this item
Full title
Author / Creator
Notomi, Shoji , Ishihara, Kenji , Efstathiou, Nikolaos E. , Lee, Jong-Jer , Hisatomi, Toshio , Tachibana, Takashi , Konstantinou, Eleni K. , Ueta, Takashi , Murakami, Yusuke , Maidana, Daniel E. , Ikeda, Yasuhiro , Kume, Shinji , Terasaki, Hiroto , Sonoda, Shozo , Blanz, Judith , Young, Lucy , Sakamoto, Taiji , Sonoda, Koh-Hei , Saftig, Paul , Ishibashi, Tatsuro , Miller, Joan W. and Kroemer, Guido
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The early stages of age-related macular degeneration (AMD) are characterized by the accumulation of basal laminar deposits (BLamDs). The mechanism for BLamDs accumulating between the retinal pigment epithelium (RPE) and its basal lamina remains elusive. Here we examined the role in AMD of lysosome-associated membrane protein-2 (LAMP2), a glycoprote...
Alternative Titles
Full title
Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina
Authors, Artists and Contributors
Author / Creator
Ishihara, Kenji
Efstathiou, Nikolaos E.
Lee, Jong-Jer
Hisatomi, Toshio
Tachibana, Takashi
Konstantinou, Eleni K.
Ueta, Takashi
Murakami, Yusuke
Maidana, Daniel E.
Ikeda, Yasuhiro
Kume, Shinji
Terasaki, Hiroto
Sonoda, Shozo
Blanz, Judith
Young, Lucy
Sakamoto, Taiji
Sonoda, Koh-Hei
Saftig, Paul
Ishibashi, Tatsuro
Miller, Joan W.
Kroemer, Guido
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6876195
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6876195
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1906643116
