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Fracture repair requires TrkA signaling by skeletal sensory nerves

Fracture repair requires TrkA signaling by skeletal sensory nerves

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6877307

Fracture repair requires TrkA signaling by skeletal sensory nerves

About this item

Full title

Fracture repair requires TrkA signaling by skeletal sensory nerves

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-12, Vol.129 (12), p.5137-5150

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Bone is richly innervated by nerve growth factor-responsive (NGF-responsive) tropomyosin receptor kinase A-expressing (TrKa-expressing) sensory nerve fibers, which are required for osteochondral progenitor expansion during mammalian skeletal development. Aside from pain sensation, little is known regarding the role of sensory innervation in bone re...

Alternative Titles

Full title

Fracture repair requires TrkA signaling by skeletal sensory nerves

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6877307

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6877307

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI128428

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