Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding p...
Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Histone variants fine-tune transcription, replication, DNA damage repair, and faithful chromosome segregation. Whether and how nucleosome variants encode unique mechanical properties to their cognate chromatin structures remains elusive. Here, using in silico and in vitro nanoindentation methods, extending to in vivo dissections, we report that his...
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Full title
Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6883791
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6883791
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1911880116