Stalled developmental programs at the root of pediatric brain tumors
Stalled developmental programs at the root of pediatric brain tumors
About this item
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Author / Creator
Jessa, Selin , Blanchet-Cohen, Alexis , Krug, Brian , Vladoiu, Maria , Coutelier, Marie , Faury, Damien , Poreau, Brice , De Jay, Nicolas , Hébert, Steven , Monlong, Jean , Farmer, W. Todd , Donovan, Laura K. , Hu, Yixing , McConechy, Melissa K. , Cavalli, Florence M. G. , Mikael, Leonie G. , Ellezam, Benjamin , Richer, Maxime , Allaire, Andréa , Weil, Alexander G. , Atkinson, Jeffrey , Farmer, Jean-Pierre , Dudley, Roy W. R. , Larouche, Valerie , Crevier, Louis , Albrecht, Steffen , Filbin, Mariella G. , Sartelet, Hervé , Lutz, Pierre-Eric , Nagy, Corina , Turecki, Gustavo , Costantino, Santiago , Dirks, Peter B. , Murai, Keith K. , Bourque, Guillaume , Ragoussis, Jiannis , Garzia, Livia , Taylor, Michael D. , Jabado, Nada and Kleinman, Claudia L.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Childhood brain tumors have suspected prenatal origins. To identify vulnerable developmental states, we generated a single-cell transcriptome atlas of >65,000 cells from embryonal pons and forebrain, two major tumor locations. We derived signatures for 191 distinct cell populations and defined the regional cellular diversity and differentiation dyn...
Alternative Titles
Full title
Stalled developmental programs at the root of pediatric brain tumors
Authors, Artists and Contributors
Author / Creator
Blanchet-Cohen, Alexis
Krug, Brian
Vladoiu, Maria
Coutelier, Marie
Faury, Damien
Poreau, Brice
De Jay, Nicolas
Hébert, Steven
Monlong, Jean
Farmer, W. Todd
Donovan, Laura K.
Hu, Yixing
McConechy, Melissa K.
Cavalli, Florence M. G.
Mikael, Leonie G.
Ellezam, Benjamin
Richer, Maxime
Allaire, Andréa
Weil, Alexander G.
Atkinson, Jeffrey
Farmer, Jean-Pierre
Dudley, Roy W. R.
Larouche, Valerie
Crevier, Louis
Albrecht, Steffen
Filbin, Mariella G.
Sartelet, Hervé
Lutz, Pierre-Eric
Nagy, Corina
Turecki, Gustavo
Costantino, Santiago
Dirks, Peter B.
Murai, Keith K.
Bourque, Guillaume
Ragoussis, Jiannis
Garzia, Livia
Taylor, Michael D.
Jabado, Nada
Kleinman, Claudia L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6885128
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6885128
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0531-7
