Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK):...
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
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Author / Creator
OAK Study Group , Rittmeyer, Achim, MD , Barlesi, Fabrice, PhD , Waterkamp, Daniel, MD , Park, Keunchil, MD , Ciardiello, Fortunato, MD , von Pawel, Joachim, MD , Gadgeel, Shirish M, MD , Hida, Toyoaki, PhD , Kowalski, Dariusz M, PhD , Dols, Manuel Cobo, MD , Cortinovis, Diego L, PhD , Leach, Joseph, MD , Polikoff, Jonathan, MD , Barrios, Carlos, MD , Kabbinavar, Fairooz, MD , Frontera, Osvaldo Arén, MD , De Marinis, Filippo, MD , Turna, Hande, MD , Lee, Jong-Seok, MD , Ballinger, Marcus, PhD , Kowanetz, Marcin, PhD , He, Pei, PhD , Chen, Daniel S, MD , Sandler, Alan, MD and Gandara, David R, Dr
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Atezolizumab is a humanised antiprogrammed death-ligand 1 (PD-L1) monoclonal antibody that inhibits PD-L1 and programmed death-1 (PD-1) and PD-L1 and B7-1 interactions, reinvigorating anticancer immunity. We assessed its efficacy and safety versus docetaxel in previously treated patients with non-small-cell lung cancer. Methods W...
Alternative Titles
Full title
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
Authors, Artists and Contributors
Author / Creator
Rittmeyer, Achim, MD
Barlesi, Fabrice, PhD
Waterkamp, Daniel, MD
Park, Keunchil, MD
Ciardiello, Fortunato, MD
von Pawel, Joachim, MD
Gadgeel, Shirish M, MD
Hida, Toyoaki, PhD
Kowalski, Dariusz M, PhD
Dols, Manuel Cobo, MD
Cortinovis, Diego L, PhD
Leach, Joseph, MD
Polikoff, Jonathan, MD
Barrios, Carlos, MD
Kabbinavar, Fairooz, MD
Frontera, Osvaldo Arén, MD
De Marinis, Filippo, MD
Turna, Hande, MD
Lee, Jong-Seok, MD
Ballinger, Marcus, PhD
Kowanetz, Marcin, PhD
He, Pei, PhD
Chen, Daniel S, MD
Sandler, Alan, MD
Gandara, David R, Dr
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6886121
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6886121
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(16)32517-X
