Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Scope and Contents
Contents
Bone morphogenetic proteins (BMPs) are secreted ligands of the transforming growth factor-β (TGF-β) family that control embryonic patterning, as well as tissue development and homeostasis. Loss of function mutations in the type II BMP receptor BMPR2 are the leading cause of pulmonary arterial hypertension (PAH), a rare disease of vascular occlusion...
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Full title
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6892941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6892941
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-54830-7
