Bile acid metabolites control TH17 and Treg cell differentiation
Bile acid metabolites control TH17 and Treg cell differentiation
About this item
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Author / Creator
Hang, Saiyu , Paik, Donggi , Yao, Lina , Kim, Eunha , Trinath, Jamma , Lu, Jingping , Ha, Soyoung , Nelson, Brandon N. , Kelly, Samantha P. , Wu, Lin , Zheng, Ye , Longman, Randy S. , Rastinejad, Fraydoon , Devlin, A. Sloan , Krout, Michael R. , Fischbach, Michael A. , Littman, Dan R. and Huh, Jun R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is unknown whether they affect adaptive immune cells such as T helper cells that express IL-17a (T
H...
Alternative Titles
Full title
Bile acid metabolites control TH17 and Treg cell differentiation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6949019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6949019
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1785-z
