Initiation of Parkinson’s disease from gut to brain by δ-secretase
Initiation of Parkinson’s disease from gut to brain by δ-secretase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lewy pathology, composed of α-Synuclein (α-Syn) inclusions, a hallmark of Parkinson’s disease (PD), progressively spreads from the enteric nervous system (ENS) to the central nervous system (CNS). However, it remains unclear how this process is regulated at a molecular level. Here we show that δ-secretase (asparagine endopeptidase, AEP) cleaves bot...
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Full title
Initiation of Parkinson’s disease from gut to brain by δ-secretase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6951265
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6951265
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-019-0241-9
